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Study points to the futility of urine tests for salbutamol doping

Salbutamol, also known as albuterol, is a medication that opens upconstrictedmedium and large airways in the lungs and is often used to treat asthma. Because high doses are suspected by some to also have an anabolic effect, its daily dosage is restricted by the World Anti-Doping Agency, which uses urine tests to determine violations. A new British Journal of Clinical Pharmacology study shows thatlarge variability in urine concentrations, however, lead toinfeasibility of determining an administered dose from a single untimed urine sample.

The authors noted that the current threshold inadvertently leads to incorrect assumptions of violation, whereas many violations will go unnoticed, especially when samples are taken long after drug administration. These issues, combined with the dubious assertion of its anabolic effect, indicate that the large effort involved in testing should be reconsidered.

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