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Clinical study: Genschere to cure patients of HIV

At the University hospital Hamburg-Eppendorf in the coming year, eight HIV to be cured-positive patients using a Genschere and stem cell therapy of your infection. The Genschere with the name Brec1 cuts out the Blueprint of the AIDS pathogen HIV from the genome of the infected cell and eliminate the Virus.

A Team of researchers from the University hospital in Hamburg (UKE), the Heinrich-Pette-Institute and the Leibniz-Institute for Experimental Virology (HPI) is currently preparing a clinical study to patients of their HIV heal infection. The HPI scientists have developed the Genschere Brec1 together with a Team of the TU Dresden. It is an enzyme, the DNA of the HIV Virus target removed carefully from the cell genome. Is used new enzyme in the context of a stem cell therapy in eight HIV-patients in the clinic for stem cell therapy of the UKE.

The Genschere could be a big step in the fight against HIV and AIDS: "For the first time, we could manage to rid patients cells permanently and precisely of HIV – a Meilenstein", Katharina Fegebank, Senator for science, research and gender equality says. The clinical study is funded with public funds in the amount of approximately 8.7 million euros.


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