A new JBMR Plus review examines the negative impacts of weight loss surgery on bone health.
The review of published studies notes that weight loss surgery can cause declines in bone mass and strength, and it is linked with an increased risk of bone fractures. Skeletal changes after surgery appear early and continue even after weight loss plateaus and weight stabilizes. Nutritional factors, mechanical unloading, hormonal factors, and changes in body composition and bone marrow fat may contribute to poor bone health.
Most studies have examined the effects of the Roux-en-Y gastric bypass procedure, which was the most commonly performed weight loss procedure worldwide until it was very recently overtaken by sleeve gastrectomy. Because sleeve gastrectomy is a newer procedure, its skeletal effects have not yet been well defined.
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